determination of the lipid profile of cord blood in neonates and its correlation with maternal age in iran

conclusions in a current study based on increasing maternal age, the hdl-c level in cord blood was decreased which is an independent risk factor for cvds in adulthood. results a statistically significant negative correlation was observed between cord blood hdl-c and maternal age (r = -0.18, p <0.01). there was no relationship between other lipids and lipoproteins with maternal age. our findings also showed the tc, tg and ldl-c mean level were significantly more and the mean level of hdl-c was significantly lower than reference value. additionally, the mean of tc and ldl-c in female neonates were significantly more than the male (p <0.01). also, there was no correlation between cord blood lipids and lipoproteins with birth weight and maternal body mass index (bmi). patients and methods this cross sectional study was done on the cord blood of 243 healthy, full-term newborn infants (114 females and 129 males). the blood was sampled from the umbilical cord immediately after a normal delivery. the serum was tested in order to determine the lipid profile including total cholesterol (tc), triglycerides (tg) and high density lipoprotein-cholesterol (hdl-c). low density-lipoprotein (ldl-c) was computed by friedewald equation. background cardiovascular diseases (cvds) are the leading cause of mortality in iran; with dyslipidemia as an important contributing risk factor. objectives to assess the early onset of dyslipidemia, our goal was to determine lipids and lipoproteins levels in cord blood and their correlation with maternal age as a first study in iran.